In the religious society of Iran, political training has always required qualitative attention to Quranic principles; However, in the contemporary religious atmosphere, dimensions of the dependence of political training on religious-based epistemology have not been seriously considered; (Problem) Also, this issue has not been placed under scientific scrutiny; Therefore, we face this question: “What are the Quranic principles of the epistemology of political training curriculum? (Question) The present article assumes that the existence of the capacity and dedication of the epistemology of the Holy Quran to political training of humans, if identified and acquired effectively, can help curriculum planners in order to set their decisions on political training based on real recognition. (Hypothesis) Thus, the present paper has been written to “explain the principles of the epistemology of curriculum for political training” (Objective) using qualitative method (analytical and interpretive) based on Quran studies. (Methodology) In the process of answering the mentioned question, relying on Quranic teachings, the results including the elicitation of the dimensions of concepts, components, and criteria of the principles of epistemology, its strategic outcomes and implications in increasing the quality the decisions of planners and experts for political training are presented. (Finding)